Aug 2026
Loss of PHD3 rescues mice from Neuroinflammation and cognitive disorders induced by lipopolysaccharide or surgical trauma.
It is demonstrated that PHD3 deficiency exerts neuroprotective effects against systemic inflammation-induced cognitive dysfunction by suppressing microglial activation, synaptic damages, and neuronal apoptosis may through NF-κB signaling.
Ji Che, Yixu Deng, Xiang Zhang et al.
· Experimental Neurology · 0 citations