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Author

Xiang Zhang

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Review Open access Oct 2026

Gut microbial and metabolic modulation in enhancing immunotherapy in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. HCC immunosuppressive tumor microenvironment limits therapeutic efficacy, while immune checkpoint inhibitors (ICI) have produced only modest response rates in many patients. Emerging evidence highlights the lack of ICI response in...

Suki Ha, Ding-Wu Li, Xiang Zhang et al. · 0 citations

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