Author

Xiangze Zeng

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#protein folding Open access Oct 2026

Cooperative nature of residue interactions in biomolecular condensates.

The presence of residue interaction cooperativity is revealed in various IDP condensates using atomistic molecular dynamics simulations using atomistic molecular dynamics simulations to reproduce experimental results of condensate physical properties, including saturation concentration, viscoelasticity, and interfacial...

Le Chen, Xiang-Yu Wu, Guo-Rong Hu et al. · Proceedings of the National... · 0 citations

Open access Aug 2026

Sequence-dependent molecular asymmetry and architecture define electric potential profiles of biomolecular condensates

Biomolecular condensates, which regulate diverse cellular processes, exhibit distinct electric potential profiles. This potential gradient between the dilute and the dense phases serves as the underlying driving force mediating the unique microenvironment and electrochemical activity of condensates. However, the molecu...

Fangke Chen, Runchen Xia, Yi-Fan Dai et al. · bioRxiv · 0 citations