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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xiang-Nan Wang

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2 papers indexed here

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Sep 2026

Optimization of AsCas12f1-Mediated Long-Term Gene Repression.

A compact and programmable epigenome editor can be utilized for long-term gene silencing, which becomes a powerful tool for biological research or biomedical applications. Here, we present an enhanced CRISPR-based epigenome editor based on deactivated AsCas12f1 (dAsCas12f1) variants, which incorporate epigenetic modula...

Yang-Yang Sun, Lin-Yung Li, Xiang-Nan Wang et al. · 0 citations
Aug 2026

MINFLUX nanoscopy links chromatin nanostructure to transcriptional state in living cells.

A central question in gene regulation is the relationship between the nanoscale organization of chromatin and transcriptional activity. However, directly visualizing and quantifying this process in living cells at nanometer resolution remains challenging. Here, we integrate live-cell MINFLUX nanoscopy with the DNA prob...

Yi Hu, C. Zuo, Xiang-Nan Wang et al. · 0 citations

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