Author

Xiang-Ming Jiang

2 papers indexed here

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Dec 2026

Paeonia lactiflora pall. Polysaccharide attenuates inflammation and improves intestinal barrier function in ulcerative colitis mice by modulating intestinal flora and inhibiting S100A8/A9/NF-κB signaling.

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) with substantial clinical burden and limited treatment options. PLPN-2, an α-glucan extracted from P. lactiflora, has shown anti-inflammatory activity in cellular and animal models, but its therapeutic mechanisms in UC remain unclear. Here, mice were...

Pei-Pei Li, Hong-Su Zhao, Xiang-Ming Jiang et al. · Food Research International · 0 citations

Open access Sep 2026

Aqueous extract of Paeoniae Radix Alba alleviates DSS-induced ulcerative colitis via inhibition of the IFN-γ/JAK1/STAT1 signaling pathway and restoration of intestinal barrier function.

BACKGROUND Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by aberrant immune activation and intestinal microenvironment dysregulation. Paeoniae Radix Alba (RPA), a classic traditional Chinese medicine (TCM) derived from the roots of Paeonia lactiflora, possesses potent anti-inflammatory,...

Rong-Yun Cao, Mei-Juan Sun, Min Pan et al. · Phytomedicine · 0 citations