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Author

Xiang-Li Tong

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2 papers indexed here

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Review Sep 2026

Irisin-BDNF axis mediates muscle-brain communication: a complete molecular cascade and potential bidirectional feedback from peripheral activation to central protection

Potential intervention strategies and the prospects for future translational research are explored, including upstream exercise interventions, midstream barrier-crossing enhancing peptides, and downstream small-molecule TrkB agonists.

Xiu-Yan Duan, Zi-Xuan Chen, Xiang-Li Tong et al. · 0 citations
Jul 2026

Effect of moderate-intensity aerobic exercise on early oxidative stress and muscle atrophy in SAMP8 mice through modulation of the DAO/SRR and Nrf2/Keap1 pathways.

It is suggested that moderate-intensity aerobic exercise alleviates early oxidative stress and muscle atrophy by inhibiting the pro-oxidant DAO/SRR pathway and activating the Nrf2/Keap1 antioxidant axis, thereby providing evidence for the molecular mechanisms underlying the attenuation of age-related skeletal muscle de...

Xiang-Li Tong, Jinkun Xue, Zi-Xuan Chen et al. · 0 citations

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