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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xiang-Hui Han

h-index 4 View on Semantic Scholar

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Review Oct 2026

Beyond the membrane: lipid rafts and oxysterols establish cholesterol as a dynamic signaling hub while underlying the cholesterol paradox in cancer.

This review addresses the paradoxical roles of cholesterol in oncology, in which cancer cells leverage oxysterols and membrane lipid rafts to promote metastasis, immunosuppression, and therapy resistance, while baseline cholesterol homeostasis remains essential for proper immune cell function.

Wei-Wei Liu, Qiong-Lian Huang, Xiang-Hui Han · 0 citations

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