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Author

Xiang Hu

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Open access Sep 2026

Lysophosphatidylcholine-induced macrophage polarization imbalance and functional dysregulation in immune thrombocytopenia.

LPC (16:0/0:0) drives ITP pathogenesis by reprogramming macrophage metabolism and function, promoting inflammation and platelet destruction, and the DXM-AT combination exerts synergistic therapeutic effects by complementary targeting of metabolic and immune pathways in the LPC-driven pathogenic axis.

Nan Jiang, Zi Sheng, Shao-Qiu Leng et al. · 0 citations

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