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Xian-Mei Qi

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Aug 2026

Development of Oligo-PROTACs That Target C/EBPα.

CCAAT/enhancer-binding protein alpha (C/EBPα) is a critical lineage-defining transcription factor and tumor suppressor. Despite its clinical significance in conditions like acute myeloid leukemia and hepatocellular carcinoma (HCC), C/EBPα has remained undruggable due to its intrinsically disordered regions and lack of...

Junming Cai, Xian-Mei Qi, Adam T. Smiley et al. · 0 citations

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