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Xian-Li He

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Open access Sep 2026

Disrupting the BEX4-Mediated DNA Repair Rheostat with a Novel Inhibitor Suppresses Stemness and Enhances Chemosensitivity in Hepatoblastoma.

Cisplatin resistance in hepatoblastoma (HB) is a major therapeutic barrier. Emerging evidence suggests that cancer cells can activate DNA double-strand break repair pathways to evade chemotherapy-induced apoptosis and sustain stemness; however, the mechanisms underlying cisplatin resistance in HB remain poorly understo...

Ze-Yu Yan, Qian Wang, Jing Li et al. · 0 citations

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