Isoxazoline insecticides exhibit broad-spectrum and highly effective insecticidal activity by acting on insect GABA receptors. Existing insecticides have high toxicity towards non-target organisms, such as bees, limiting their practical use. This study utilized an active group splicing approach to create 41 new isoxa...
Zhong-Lu You, Bo-Yi Sun, Zheng-Wei Wu et al.· Journal of Agricultural and...· 0 citations
Peanut stem rot, caused by the soil-borne pathogen Sclerotium rolfsii, poses a significant threat to global peanut production and results in substantial yield losses. A series of thiocarbamate derivatives were synthesized and evaluated against ten phytopathogenic fungi. Over 50% showed broad-spectrum fungicidal activ...
Rong Li, Yuan-Jian Huang, Min Ge et al.· Journal of Agricultural and...· 0 citations
To develop eco-friendly succinate dehydrogenase inhibitors with good fungicidal activity, various diaryl-substituted thiazole-2-carboxamide derivatives were designed and synthesized based on structure-activity relationships (SARs) and molecular docking. At 20 mg/L, most target compounds exhibited ≥80% inhibition agains...
Chao Zhang, Min Ge, Yuan-Jian Huang et al.· Journal of Agricultural and...· 0 citations
A1 and A2 are identified as promising, bee-safe leads for next-generation SDHI fungicides based on a 3,5-dichloro-2,6-difluoropyridin-4-amine scaffold and disrupt mycelial morphology and inhibit SDH, supported by molecular docking and enzyme activity assays.
Bo-Yi Sun, Hui Wang, Dan-Dan Wang et al.· Journal of Agricultural and...· 1 citation
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