Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy
A surface display strategy is utilized to construct an adhesion‐enhanced Escherichia coli Nissle 1917 chassis that effectively alleviates inflammation, restores epithelial barrier integrity, and reverses oxidative damage in both prophylactic and therapeutic murine colitis models.
Yu-Xi Wang, Pei-Chao Zhang, Si-Min Gu et al.
· Advancement of science · 0 citations