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Xi-Zhuang Gao

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Open access Aug 2026

Potential hazard assessment of 6PPD-quinone in the context of ulcerative colitis: network toxicology, machine learning, transcriptomic analysis, and preliminary In vivo validation

In vivo experiments demonstrated that 6PPD-Q exposure significantly exacerbated DSS-induced colonic shortening, macroscopic lesions, and histopathological damage, and provided an integrative mechanistic framework for investigating the potential intestinal effects of 6PPD-Q under inflammatory conditions.

Jing-Yi Li, Xi-Zhuang Gao, Ye-Min Xu et al. · 0 citations

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