Open access
Aug 2026
Spatial transcriptomic analysis identifies a necroptosis-prone thyroid follicular cell state in Hashimoto’s thyroiditis
This study provides a multimodal characterization of necroptosis in HT, showing that the inflammatory immune microenvironment is associated with TFC loss and activation of an RIPK3-MLKL-predominant necroptosis-related program, without detectable upregulation of total or phosphorylated RIPK1.
Dong-Yu Yang, Cihang Lu, Weiping Teng et al.
· Frontiers in Immunology · 0 citations