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Author

Xavier Pivot

2 papers indexed here

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Open access Aug 2026

Innovative Dose–Response Assessment of the Metaboreflex With Indirect Control of Intramuscular Metabolic Perturbation in Humans

We aimed to evaluate an innovative dose–response approach to assess the metaboreflex with control of intramuscular metabolic perturbation (concept of metaboreflex gain). We also investigated potential sex differences in the metaboreflex using this new approach.

Nabil Kouzkouz, J. Mallard, E. Hucteau et al. · 1 citation
Open access Jul 2026

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Antibody–drug conjugates (ADCs) are often described as simple carriers that shuttle cytotoxic payloads to tumors. However, many backbones, exemplified by trastuzumab, are potent biologics whose pharmacology is eroded by conjugation. In this Perspective, we introduce the concept of an antibody exposure deficit. This rep...

Xavier Pivot, Sebastian Jung, S. Harlepp et al. · 0 citations

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