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Open access Oct 2026

FOXA1+CD3+T lymphocytes exacerbate myocardial injury in immune checkpoint inhibitor associated myocarditis via the DLL1/Notch1/GSDMD signaling pathway

Immune checkpoint inhibitor-associated myocarditis (ICIAM),through occurring in only 1%-1.4% of patients, carries a mortality rate of up to 60%. Despite this high lethality, its pathogenesis remains poorly understood. While T cell-driven inflammation is a known feature of ICIAM, the key transcriptional regulators...

X. Liu, J.-Q. Li, C.-H. Guo et al. · 0 citations

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