Author

X. Li

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#protein folding Open access Oct 2026

Long Non-Coding RNA LINC01614 Promotes Aggressive Phenotypes and Ferroptosis Resistance in Papillary Thyroid Cancer Through a Putative miR-4521/IGF2/PI3K-AKT Signaling Axis

Background/Objectives: Papillary thyroid cancer (PTC) is the most common endocrine malignancy and is generally associated with favorable clinical outcomes. However, a subset of tumors develops aggressive phenotypes characterized by increased proliferation, migration, therapeutic resistance, and disease progression. Lon...

D. Quaranto, N. DeSouza, Michelle Carnazza et al. · Genes · 0 citations

Review Open access Aug 2026

Convergent Mechanistic Pathways Driving the Anaplastic Phenotype in Thyroid Cancer

The principal mechanistic programs that define the ATC phenotype are described: disruption of cell-cycle and apoptotic control through alterations in TP53, CDKN2A/B, and aberrant MAPK activation; metabolic adaptations involving glycolysis, glutaminolysis, and mitochondrial one-carbon metabolism; reprogramming of canoni...

Anthony Centone, N. DeSouza, Nan Yang et al. · International Journal of Mol... · 0 citations