Open access
Sep 2026
N-Acetylcysteine Attacks Phenoloxidase to Inhibit Insect Melanization and Boost Fungal Virulence
The prophenoloxidase (PPO) melanization cascade is a cornerstone of insect humoral immunity against fungal pathogens, yet its direct fungicidal mechanism remains undefined, and strategies to safely manipulate this pathway for biological control are lacking. Here, we demonstrate that infection of Drosophila by the entom...
Ying-Yu Tang, Yu-Yang Lian, Shi-Rong Li et al.
· Journal of Fungi · 0 citations