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Author

Wouter H. Roos

2 papers indexed here

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Open access Sep 2026

Effect of liposome rigidity on corona formation and its implications for uptake by cells

Nanoparticle rigidity influences cellular uptake and in vivo behavior, yet the underlying mechanisms remain unclear. Here we used lipids with identical head groups but different acyl chains to prepare liposomes with comparable surface composition, size and zeta potential, but distinct mechanical properties. Rigid lipos...

Xin-Yu Ma, Feng Zhao, Miguel Cantero-Reviejo et al. · 0 citations
Open access Sep 2026

Inositol Hexakisphosphate Promotes Open Pore State in HIV Capsid Protein Lattice by Reconfiguring Subunit Contacts

IP6 is established as a proviral regulator that couples nanoscale pore dynamics, intersubunit contact reconfiguration, and mechanical resilience of the HIV-1 capsid, providing a unified mechanistic framework for its role in viral replication.

Y. Knelissen, Judith Escrig, Amanda C. Macke et al. · 0 citations

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