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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

William I. Weis

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2 papers indexed here

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Open access Oct 2026

Glycan-mediated binding to collagen by a C-type lectin-like domain of the endocytic receptor Endo180 / uPARAP.

The primary role of the multidomain endocytic receptor designated Endo180 or uPARAP (urokinase-plasminogen activator receptor associated protein) is to facilitate internalization of collagen for lysosomal degradation during matrix remodeling in tissues. However, Endo180 interacts both with collagen and sugars and the r...

K. Drickamer, S. A. F. Jégouzo, H. Feinberg et al. · 0 citations
Open access Sep 2026

Mechanical opening of the αE-catenin M-region gates afadin condensation in cardiomyocytes

In mechanically active tissues, cell-cell adhesions must withstand high and dynamic loads to maintain tissue integrity. The ability to detect and withstand load centers on the mechanosensitive adherens junction (AJ), which couples the actin networks of adjacent cells. The mechanosensor αE-catenin responds to force by o...

S. Pokutta, Yerin Han, Korina I. Karpov et al. · 0 citations

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