La-Ribo: RNA Co-Design via Geometry-Latent Flow Matching
RNA function arises from the coupling of nucleotide sequence and three-dimensional structure, motivating their joint design. Coordinating global folding with nucleotide-level detail remains challenging under limited structural supervision. We introduce La-Ribo, a generative framework for RNA sequence-structure co-desig...
Run-Ze Ma, William Hua, Shuang-Jia Zheng
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