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Author

Wesley B. Asher

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Open access Sep 2026

G protein diffusion states reveal receptor binding dynamics at single-molecule scale

It is suggested that native GPCR-G protein interactions are not resolved at 15 ms time resolution and a diffusion-based approach is established for studying receptor-G protein kinetics in living cells.

Signe Mathiasen, Jozsef Meszaros, Chase M. Webb et al. · 0 citations
Open access Jul 2026

Dopamine D2 receptors bypass canonical signaling to directly tune NMDA receptor function and aversive learning

It is shown that D2Rs can bypass second messenger systems to tune glutamatergic transmission through receptor-receptor interactions, providing a mechanism by which dopamine selectively gates specific glutamatergic inputs to control striatal plasticity and behavioral adaptation.

Sheng Gong, J. Adler, Ying Zhu et al. · 0 citations

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