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Author

Weronika Zając

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Review Open access Sep 2026

Supportive organ management in acute right ventricular failure secondary to pulmonary embolism: a narrative review

The pathophysiology of ARVF in PE and available supportive strategies are reviewed, appraising their efficacy, safety and evidence quality, and management of ARVF in PE demands combined causal and supportive treatment.

Aleksander Urbaś, Małgorzata Wandzel, J. Wandzel et al. · 0 citations
Open access Aug 2026

mTORC1 inhibition upregulates CD20 and enhances anti-CD20 antibody efficacy in B-cell precursor acute lymphoblastic leukemia.

It is demonstrated that overexpression of wild-type IKZF1, a tumor suppressor frequently mutated in high-risk BCP-ALL, upregulates CD20 and promotes leukemic B cell maturation, and the use of mTORC1 inhibitors to sensitize BCP-ALL cells to CD20-directed immunotherapies is supported.

Agnieszka Dąbkowska, Martyna Janowska, Agata Pastorczak et al. · 0 citations

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