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An overview of the current landscape of novel biological therapeutics and their molecular targets is provided, highlighting both the progress achieved and the ongoing challenges in optimizing targeted therapies for Crohn’s disease.
Background: Obesity has become a global civilization-related disease and constitutes an independent risk factor for numerous somatic disorders. Obesity can contribute to depression through low self-esteem, body image concerns, and stigmatization, while depression and chronic stress may promote obesity through emotional...
Wearable devices offer acceptable accuracy for step counting and heart rate but not energy expenditure, and standardized validation protocols, algorithmic transparency, and long-term effectiveness studies are needed to maximize clinical and sporting utility.
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