Author

Wen-Jun Huang

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Sep 2026

Abstract A005: Preliminary results from STRIvE-01, Arm B: A phase I study of EGFR806 x CD19 CAR T cell immunotherapy for recurrent/refractory solid tumors in children and young adults

The epidermal growth factor receptor (EGFR) is associated with aggressive neoplastic disease, chemotherapy resistance, and increased metastatic potential in solid neoplasms. Approximately 20-30% of pediatric solid tumors (ST) express EGFR, enriched for soft tissue sarcomas (STS). The unique EGFR monoclonal antibody (...

Catherine M. Albert, N. Pinto, Molly R. Taylor et al. · Cancer Research · 0 citations

Jul 2026

An epigenetic polarity governing T cell tolerance for commensal microbiota 2250947

The study depicts an epigenetic polarity governing Treg-mediated immune tolerance, highlighting a fundamental asymmetry at the epigenetic level that differentially regulates Treg and conventional T cells.

Wenjun Huang, Yongqiang Feng, Jun Li et al. · Journal of Immunology · 0 citations