Design, Synthesis, and Evaluation of Novel Cephalotaxine-Cinnamic Acid Derivatives Against Hepatocellular Carcinoma
Cephalotaxine (1) is a parent compound within the cephalotaxine alkaloids class mainly derived from Cephalotaxus plants. In this study, by coupling 1 with cinnamic acid, 17 novel cephalotaxine-cinnamic acid derivatives (S1–S17) were designed and synthesized to enhance their anti-tumor efficacy. Among them, S10 showed t...
Wenxing Li, Yiming Qian, Hao Wang et al.
· Molecules · 0 citations