Review
Open access
Jul 2026
MYC in Oncogenesis and Therapeutic Implications
This review synthesizes emerging insights into MYC orchestrated tumor microenvironment remodeling, reciprocal regulation with noncoding RNAs, and the transcriptional and epigenetic governance of metabolic reprogramming to posit MYC as a highly multidimensional regulatory node whose context‐dependent functions present both formidable challenges and promising new opportunities for effective therapeutic intervention.
Na Zhang, Li Wei, Cui-Ping Tang et al.
· MedComm · 0 citations