Author

Wen Zhu

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#protein folding Sep 2026

Label-free colorimetric immuno-RCA with Tyndall effect readout.

This work describes a label-free colorimetric immunoassay that initially integrates rolling circle amplification (RCA) with Tyndall effect (TE) characteristics of nucleic acid colloids. Using only a laser pointer and a smartphone, it achieves instrument-free protein quantification with 13-fold higher sensitivity than the conventional optical ELISA.

Jia-Rui Li, Wenli Zhu, Karuna D. Chen et al. · Chemical Communications · 0 citations