Author

Wenyuan Wang

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Open access Oct 2026

Single-Dose Intrathecal rAAV2-Retro Delivering Anti-hSOD1 miRNA Confers Robust Neuroprotection in Adult ALS Mice

Amyotrophic lateral sclerosis (ALS) kills within a few years of onset, and the drugs licensed for treatment change that course only marginally. Silencing SOD1 has become a credible treatment route, but two gaps hold this approach back: an efficient vector platform for spinal cord transduction with limited peripheral tr...

Xue-Qi Gong, Hao Wei, Lang Shen et al. · Cells · 0 citations

Open access Aug 2026

Preliminary transcriptome profiling of induced pluripotent stem cell-derived hematopoietic stem and progenitor cells in Kawasaki disease

iPSC-derived HSPCs from patients with KD display altered immune-inflammatory transcriptional profiles and suppressed B-cell developmental signatures at the transcriptomic level, which suggest that early hematopoietic immune dysregulation may contribute to KD pathogenesis.

Lian-Ni Mei, Lei Gao, Rui-Zhi Zhang et al. · Frontiers in Pediatrics · 0 citations