Open access
Aug 2026
Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer
ABSTRACT The efficacy of chemotherapy in colorectal cancer (CRC) is closely linked to its ability to remodel the tumor immune microenvironment (TIME), though the underlying molecular determinants remain incompletely defined. Here, we identified tumor‐cell intrinsic autophagy as a pivotal orchestrator of an immunologica...
B. Cheng, Chaoying Wei, Zhitong Niu et al.
· Advancement of science · 0 citations