NETosis-PANoptosis Crosstalk in Colitis-Associated Colorectal Cancer: Mechanistic Links, Biomarkers, and Therapeutic Prospects
Abstract Colitis-associated colorectal cancer (CAC) is a serious long-term complication of inflammatory bowel disease (IBD) that develops through a chronic inflammation–dysplasia–carcinoma sequence. Persistent mucosal inflammation promotes epithelial barrier disruption, oxidative and genotoxic stress, dysregulated repa...