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Wen-Ting Dong

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Review Open access Aug 2026

Engineered strains as living factories: efficient biosynthesis and modification of natural products via synthetic biology and one-pot chemical tandem reactions

This review addresses the central question of how biosynthetic precision and chemical diversification can be coupled when conventional metabolic engineering alone cannot fully overcome low titers, enzyme promiscuity limits, intermediate toxicity, and scale-up heterogeneity.

Sha Liu, Pan Chen, Hai-Tao Li et al. · 0 citations

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