ABSTRACT African swine fever (ASF) is a highly pathogenic swine infectious disease caused by African swine fever virus (ASFV), with a mortality rate approaching 100% in domestic pigs and causing severe economic losses to the global pig industry. Despite the recent approval of live-attenuated ASF vaccines in limited reg...
Xing-Lin He, Hong Li, Rui-Qing Yang et al.· Emerging Microbes and Infect...· 0 citations
African swine fever virus (ASFV), a large double-stranded DNA virus, poses one of the most significant infectious disease threats to the global swine industry. ASFV transcription is particularly complex because of its unique host-independent transcription system. Using nanopore sequencing technology, we accurately iden...
Gui-Qian Wang, Peng-Fei Li, Xing-Lin He et al.· PLoS Pathogens· 0 citations
Nanotechnology has demonstrated transformative potential across molecular diagnostics, targeted drug delivery, and vaccine development; yet the majority of nanoparticle systems that show promise in preclinical settings fail to achieve clinical approval, a translational attrition rate that reflects systematic design g...
A. Ghonaim, Marwa Ahmed El-Naka, W. Nageeb et al.· BMEMat· 0 citations
ABSTRACT Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen that causes severe diarrhea, vomiting, and dehydration in piglets, and a recent human infection report raises concerns about its zoonotic potential. The S1 subunit of the PDCoV-spike protein is the primary target of neutralizing antibodies and is...
Jia-Ru Zhou, Ran Jing, Meng-Di Zhang et al.· mBio· 0 citations
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