Wen-Mo Liu

An oncolytic virus armed with fowl adenovirus fiber-modified recombinant TRAIL enhances tumor targeting and immunotherapy activity.

Oncolytic viruses have emerged as a promising strategy in cancer immunotherapy and have been applied to the treatment of various tumors. We previously demonstrated that oncolytic adenoviruses engineered expressing tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) could induce apoptosis in tumor cells and...