Author

Wenli Zhang

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Review Open access Sep 2026

Therapeutic potential of oncolytic viruses in hematopoietic malignancies: from preclinical insights to clinical realities

While certain forms of lymphoma—such as classical Hodgkin lymphoma—are classified as curable, with over half of all patients achieving remission following first-line therapy, a significant proportion of patients still suffer from relapsed or refractory disease. Through autologous stem cell transplantation (ASCT) and ch...

Sebastian Erkens, Dawit Belai Ghebrehiwot, Julius Knierer et al. · Frontiers in Microbiology · 0 citations

Review Jul 2026

Helper-Dependent Adenoviral Vectors: Recent Advances and Emerging Applications

Helper-dependent adenoviral vectors (HDAdVs), which lack all viral coding sequences, enable the delivery of up to 35 kilobases (kb) of therapeutic DNA into target cells. This large packaging capacity facilitates the transfer of complex, large, or even multiple transgenes. Despite the technical complexity of their produ...

Montaha Alshawabkeh, Eric Ehrke-Schulz, Wenli Zhang et al. · Human Gene Therapy · 0 citations