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Author

Wen Li

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Open access Sep 2026

Integrating network analysis and machine learning to explore the pharmacological targets and associations of oleanolic acid in lung adenocarcinoma

This study identifies ALOX5AP and TOP2A as potential pharmacological biomarkers associated with OA treatment in LUAD and establishes a pharmacological and theoretical foundation for understanding OA’s anti-tumor effects and future therapeutic potential.

Ying Zeng, Hong-Ting Jiang, Fei Zhang et al. · 0 citations
Open access Aug 2026

Mut-p53 acts as a synthetic lethal partner with E2F3 inhibition in gastric cancer under FGFR1 inhibitor.

This study demonstrates that FGFR1 inhibition induces synthetic lethality in mutant p53 gastric cancer by targeting the E2F3 axis, and suggests that S29 provides a strategic therapeutic approach for patients with TP53 mutations.

Si-Jia Zhong, Fanxi Meng, Leyu Wan et al. · 0 citations

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