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Author

Wen-Jun Zhao

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Aug 2026

The mechanism of SOX4/IGF2BP3/TRIB3 axis inhibiting autophagy and aggravating liver injury in sepsis.

It was found that the SOX4/IGF2BP3/TRIB3 axis was upregulated in septic hepatocytes, and its knockdown alleviated LPS-induced injury and impaired autophagic flux, and this axis exacerbated LPS-induced hepatocyte injury by suppressing autophagic flux.

Wen-Jun Zhao, Jing Zhang, Liang Zhang et al. · 0 citations
Open access Sep 2026

Prognostic Value of VPS45 in HCC and Its Correlation with Immune Microenvironment

The biological role of VPS45 in hepatocellular carcinoma (HCC) is clarified and, through comprehensive database analyses combined with in vitro experiments, supports its potential as a diagnostic and predictive biomarker for HCC.

Ji-Ming Duan, Wen-Jun Zhao, Na Lv et al. · 0 citations

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