This review examines the roles of four key frontiers, including organoid models, gene editing, AI-driven molecular design, and synthetic biology, and discusses how these technological frontiers contribute to disease modeling, target discovery, molecular design, and translational innovation.
Porcine epidemic diarrhoea virus (PEDV) is a highly contagious enteric coronavirus causing acute watery diarrhoea and high mortality in neonatal piglets, threatening the global swine industry. In recent years, GIIc subtype PEDV has spread rapidly across China via natural recombination and antigenic drift, undermining c...
Jinpeng Fan, Yan-ling Liu, Wenqian Fu et al.· BMC Veterinary Research· 1 citation· ⚡1
This study generated and characterized a panel of monoclonal antibodies targeting the PDCoV S1 protein and identified five S1B-specific neutralizing antibodies that cross-react with S1B proteins from multiple human- and avian-origin deltacoronavirusess.
Jia-Ru Zhou, Ran Jing, Meng-Di Zhang et al.· mBio· 0 citations
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