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Author

Wen-Jing Liu

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Open access Sep 2026

Photoinitiator-free gelatin hydrogel microneedles for acute gouty arthritis treatment

Photo-crosslinked microneedles (MNs) are widely used in biomedical applications, but their dependence on exogenous photoinitiators continues to pose a fundamental challenge to their further advancement. Herein, we have developed a hydrogel MN system loaded with self-assembled nanoparticles (NPs). The NPs are composed o...

Jian-Hua Zhang, Heng-Jie Zhang, Tian-You Wang et al. · 0 citations
Oct 2026

Carboxymethyl chitosan-sodium alginate/carboxymethyl cellulose pH-responsive efficient drug-loaded gel for the treatment of inflammatory bowel disease.

Budesonide offers potent anti-inflammatory activity and high first-pass metabolism for oral IBD therapy, but existing dosage forms suffer from gastric leakage and intestinal burst release. pH-responsive hydrogel faces a fundamental trade-off: high crosslinking ensures encapsulation yet suppresses release, whereas low c...

Ting-Jian Weng, Wen-Jing Liu, Yue Zeng et al. · 0 citations

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