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Author

Wen-Jie Xu

1 paper indexed here

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Oct 2026

Dehydrocostus lactone attenuates sepsis-associated neuroinflammation by directly targeting JAK2 identified through thermal proteome profiling.

Investigation of the protective effects and target mechanism of DL on CLP-induced septic mice and LPS-stimulated BV2 microglia found it suppressed JAK2 phosphorylation and downstream STAT3 activation, thereby inhibiting neuroinflammatory responses.

Xue-Ling He, Ting Zhang, Xue-Ting Chen et al. · 0 citations

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