Pinocembrin alleviates tubular inflammatory fibrosis and glomerular mesangial lesions in diabetic nephropathy through HSP90AB1/TGF-β1/Smad3 and VEGFR/ERK signaling
Diabetic nephropathy (DN) ranks as the primary contributor to end-stage renal disease across the globe, characterized by progressive glomerular mesangial proliferation and tubular interstitial fibrosis, which poses a severe threat to public health. Pinocembrin is a major flavonoid compound that has been reported to exh...