Open access
Sep 2026
Targeting the PCSK9–PR–IL-17 axis for psoriasis therapy
Psoriasis is a chronic, immune-mediated inflammatory dermatosis characterized by keratinocyte hyperproliferation and systemic metabolic comorbidities. Although proprotein convertase subtilisin/kexin type 9 (PCSK9) is a well-established regulator of lipid metabolism, its role in the cutaneous inflammatory microenvir...
Yan Li, Ying-Xue He, Sheng-Wei He et al.
· Frontiers in Pharmacology · 0 citations