Metal-sulfur metabolic derangement and regulated cell death in age-related cardiovascular diseases: mechanisms, biomarkers, and emerging interventions.
This review integrates iron-, copper-, and sulfur-metabolism-related RCD programmes across shared pathological interfaces, disease-specific contexts, and translational opportunities and highlights circulating metal and thiol/disulfide indices, transcriptomic signatures, lesion-responsive nanomedicine, and imaging platf...