Wen-Fei Xu

Self‐Enhancing Photodynamic / Immunotherapy via a MOF Nanoplatform for Combined STING Activation and Immune Checkpoint Blockade

A cascade‐amplified photodynamic immunotherapy nanoplatform based on the core‐shell structured metal‐organic frameworks (MOFs) was elaborately constructed, offering a powerful and translatable approach to expand the scope of cancer immunotherapy.

Pharmacological intersections between type 2 diabetes and cancer: metabolic crosstalk, antidiabetic therapies, and clinical implications.

This review synthesizes epidemiological and mechanistic evidence linking T2D with cancer and evaluates the oncological implications of major antidiabetic therapies and critically examine metformin, insulin analogs, sulfonylureas, sodium-glucose cotransporter 2 inhibitors, thiazolidinediones, dipeptidyl peptidase-4 inhi...

An XNA-CRISPR Platform for PAM-Free Detection of the katG Ser315Thr Mutation Associated with Isoniazid Resistance in Tuberculosis

Drug-resistance Tuberculosis (TB) is a major threat to global public health. Simple and precise detection of the mutations associated with drug resistance is still a significant challenge. CRISPR-based nucleic acid detection has emerged as a transformative technology in molecular diagnostics due to its high specifici...

Long non-coding RNA SNHG6 promotes the proliferation of PASMCs cells through the miR-429/DUSP1 axis during early/subacute vascular responses to pulmonary embolism.

FOXD3 Is Functionally Linked to NF-κB Signaling in KRAS G12C-Mutant NSCLC Cells

Findings support a functional association between FOXD3 overexpression and reduced NF-κB-related transcriptional activity in KRAS G12C-mutant NSCLC models, although the present data do not establish direct causal mediation by NF-κB.