Author

Wen Dang

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Oct 2026

Guaianolide-type sesquiterpenes from Rhaponticum repens (L.) Hidalgo with anti-ischemic stroke activity.

Ischemic stroke (IS) is a severe central nervous system disorder with high mortality and disability rates, and microglia-mediated neuroinflammation exacerbates ischemic brain injury. In this study, the traditional ethnic medicine Rhaponticum repens (L.) Hidalgo was found to significantly inhibit lipopolysaccharide (LPS...

Ye-Wen Jia, Wen Dang, Jia-Yi Du et al. · Bioorganic chemistry (Print) · 0 citations

Open access Sep 2026

Genotype II Live‐Attenuated ASFV Vaccine Bearing 24 Genes Deletion in 3 Independent Regions Is Able to Provide Complete Protection Against Homologous Lethal Challenge

The results indicate that ASFV‐Δ24 can be used as an effective and promising candidate vaccine to control the spread of ASFV.

Fan Xu, Wen Dang, Yu Du et al. · The FASEB Journal · 0 citations

Open access Jan 2026

IRES Mutation Confers a Replicative Advantage to SVA by Enhancing Translation Efficiency

This study aimed to characterize the mutational and evolutionary patterns of the SVA genome during its transmission within host cells exhibiting enhanced innate immunity, and indicated that the mutant virus was unable to evade host antiviral innate immunity, whereas it significantly enhanced the translational activity...

Tao Li, Wen Dang, Wei-Wei Li et al. · Transboundary and Emerging D... · 0 citations

Open access Jul 2026

MGF100 but not MGF300 family is a potential multigene-deleted target for ASFV attenuation and live attenuated vaccine development

The MGF100 family is a potential multigene-deleted target for ASFV live-attenuated vaccine development and was found to be capable of inducing a robust innate immune response in vitro and a consistent P30 antibody response in vivo.

Wen Dang, Fan Xu, Yu Du et al. · Virulence · 0 citations