Author

Wen-Bo Zhang

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Open access Sep 2026

Treatment modalities and survival outcomes among elderly patients with stage IV small-cell lung cancer and synchronous brain metastases: A retrospective seer-based cohort study.

OBJECTIVE Chemotherapy improves survival in patients with lung cancer. However, the prognostic associations linked to chemotherapy remain unclear in elderly patients with stage IV small-cell lung cancer (SCLC) and brain metastases. This retrospective study was performed to explore the prognostic associations of differe...

Wen-Bo Zhang, Jian-Wei Gu, Xiao-Jun Xiang et al. · Cancer Treatment and Researc... · 0 citations

Sep 2026

Targeting PPP1R14B overcomes immunotherapy resistance in prostate cancer by restoring CD8+ T-cell infiltration via the Nrf2/CX3CL1 axis.

PPP1R14B (PP1 regulatory inhibitor subunit 14B) was overexpressed in PCa and associated with poor prognosis, promoting PCa cell proliferation, suppressing apoptosis, and correlating with increased tumor purity but reduced CD8+ T-cell infiltration.

Jie Yang, Chuan Zhou, Wen-Bo Zhang et al. · Journal of Pathology · 0 citations

Review Open access Aug 2026

The predictive value of abnormal uteroplacental and fetal Doppler indices for adverse perinatal outcomes in hypertensive disorders of pregnancy: a systematic review and meta-analysis

Abnormal uteroplacental and fetal Doppler indices, particularly UtA-PI and CPR, are strongly associated with adverse perinatal outcomes in HDP patients and are recommended as a multi-parametric, sequential monitoring workflow for HDP management.

Peng Zhou, Zhong-Feng Tang, Si-Yuan Li et al. · Frontiers in Medicine · 0 citations