Background: Accessible biomarkers are needed to complement conventional clinicopathological risk assessment in endometrial cancer. Calreticulin (CALR) and heat shock protein 70 (HSP70) are stress-related proteins involved in immunogenic cell death and tumor–immune interactions, but their clinicopathological and prognos...
Xue-Qin Xiang, Xiaoqing Yin, Wen-Bin Zhan et al.· Frontiers in Oncology· 0 citations
Neuregulin 1 (NRG1), as a key ligand of the epidermal growth factor receptor family, plays a crucial role in the initiation, progression, and metastasis of various solid tumors by binding to human epidermal growth factor receptor 3 (HER3) and activating downstream signaling pathways. In recent years, NRG1 gene fusions...
Yue Zhao, Yuting Yong, Yuan-Shuai Li et al.· Cancer Plus· 0 citations
Although standard therapies including surgery, radiotherapy, and chemotherapy have proven effective in the initial eradication of primary tumors, a substantial proportion of cancer patients remain at persistent threat of recurrence. Accumulating evidence identifies tumor dormancy as a pivotal driver of this clinical ch...
Yuan-Shuai Li, Wen-Bin Zhan, Min Min et al.· Frontiers in Medicine· 0 citations
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