Author

Weiyun Shen

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Jul 2026

IGFBP5 suppresses colorectal cancer stemness and carcinogenesis via binding to GPR182 and inhibiting PKCα/AKT/P70S6K axis.

Mechanistic investigations elucidate the suppressive role of IGFBP5 in colorectal cancer (CRC) stem cells via GPR182/PKCα/AKT/AKT/P70S6K axis, highlighting IGFBP5 implementation a promising strategy for CRC.

Ying He, Yuan-jia Ren, Xin-bo Li et al. · Biochemical Pharmacology · 0 citations