Open access
Jul 2026
CRM‐1 Aggravates Stroke Injury by Promoting BANF1‐Mediated Unfolded Protein Response Through Inducing Nuclear Export of ALKBH5
The activation of endoplasmic reticulum stress (ERS), specifically the PERK/eIF2α/CHOP signaling, is a recognized consequence of ischemic stroke. However, the roles and mechanisms of CRM‐1 regulating ERS in stroke are poorly elucidated. A murine model of stroke was generated via transient middle cerebral artery occlusi...
Chujuan Liu, Chen Li, Tingting Hu et al.
· The FASEB Journal · 0 citations