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Wei Yang

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Open access Oct 2026

UBA6 confers neuroprotection against sepsis-associated encephalopathy through facilitating LCN2 ubiquitin-dependent degradation.

Sepsis-associated encephalopathy (SAE) is a common secondary complication of sepsis, accompanied by neuroinflammation and neuronal apoptosis. As an E1 ubiquitin-activating enzyme, ubiquitin-like modifier-activating enzyme 6 (UBA6) deficiency aggravates inflammation. Herein, we first confirmed that UBA6 is decreased in...

Wei Yang, Xi-Han Che, Rui Ding et al. · 0 citations

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